Kinomics

Approaches and Applications
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Genre: Science
Original Publish Date: Aug 11, 2015
Product Number: EB00624320
Released: Oct 06, 2015
Business Term: Purchase
ISBN: #9783527683055
Publisher: Wiley-VCH
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Description

Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result is a toolbox for every kinase researcher: By addressing and comparing current approaches to the study of kinase action, both novice and established researchers will benefit from the practical knowledge contained in this invaluable reference.

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